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Ellen S Shang

from Calabasas, CA
Age ~57

Ellen Shang Phones & Addresses

  • Calabasas, CA
  • Beverly Hills, CA
  • Honolulu, HI
  • Los Angeles, CA
  • Keizer, OR
  • Rosemead, CA
  • Quincy, MA
  • 23016 Peacock Ct, Calabasas, CA 91302

Resumes

Resumes

Ellen Shang Photo 1

Ellen Shang

Ellen Shang Photo 2

Ellen Shang

Publications

Us Patents

Leptospira Rare Outer Membrane Proteins

US Patent:
6699482, Mar 2, 2004
Filed:
Nov 13, 2001
Appl. No.:
09/992807
Inventors:
David A. Haake - Culver City CA
Ellen S. Shang - Los Angeles CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 3902
US Classification:
4242341, 4241901, 435 691, 435 693, 435 711, 530300, 530350, 536 237
Abstract:
The present invention presents novel leptospiral membrane lipoproteins, LipL1 and LipL2, associated with pathogenic strains of Leptospira. LipL1 is of about 35 kDa, and LipL2 is of about 41 kDa. Also disclosed are the method for purifying these proteins from Leptospira, their nucleotide and amino acid sequences, the cloning of the genes encoding the proteins and their recombinant proteins, methods for producing antibodies to these proteins, the resulting antibodies. These proteins, their immunogenic fragments, and antibodies against them, are useful for inducing an immune response to pathogenic Leptospira as well as providing a diagnostic target for leptospirosis.

Leptospira Membrane Proteins

US Patent:
58372636, Nov 17, 1998
Filed:
May 19, 1995
Appl. No.:
8/444646
Inventors:
David A. Haake - Culver City CA
Ellen S. Shang - Los Angeles CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 3902
C12P 2102
C07K 100
US Classification:
4242341
Abstract:
The present invention presents novel leptospiral membrane lipoproteins, LipL1 and LipL2, associated with pathogenic strains of Leptospira. LipL1 is of about 35 kDa, and LipL2 is of about 41 kDa. Also disclosed are the method for purifying these proteins from Leptospira, their nucleotide and amino acid sequences, the cloning of the genes encoding the proteins and their recombinant proteins, methods for producing antibodies to these proteins, the resulting antibodies. These proteins, their immunogenim. fragments, and antibodies against them, are useful for inducing an immune response to pathogenic Leptospira as well as providing a diagnostic target for leptospirosis.

Borrelia Burgdorferi Outer Membrane Proteins

US Patent:
61531944, Nov 28, 2000
Filed:
Oct 29, 1998
Appl. No.:
9/183217
Inventors:
Jonathan T. Skare - College Station TX
Ellen S. Shang - Calabasas CA
Cheryl I. Champion - Los Angeles CA
David R. Blanco - Calabassas CA
James N. Miller - Northridge CA
Michael A. Lovett - Los Angeles CA
Tajib A. Mirzabekov - Newton MA
Bruce L. Kagan - Pacific Palisades CA
Paul Tempst - New York NY
Denise M. Foley - Orange CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 3900
A61K 3902
G01N 33554
C07K 100
US Classification:
4241841
Abstract:
The present invention presents three B. burgdorferi membrane proteins: Oms28, Oms45, and Oms66, each of about 28, 45, and 66 kDa respectively; and with average single channel conductances of about 0. 6, 0. 22, and 9. 7 nS, respectively. Also disclosed are the methods for purifying these proteins from B. burgdorferi, methods for producing antibodies to these proteins, and the resulting antibodies. These proteins and their immunogenic fragments, and antibodies capable of binding to them are useful for inducing an immune response to pathogenic B. burgdorferi as well as providing a diagnostic target for Lyme disease. Further disclosed are the nucleotide and amino acid sequences, the cloning of the genes encoding the proteins and their recombinant proteins, and methods for obtaining the foregoing. Other B. burgdorferi outer membrane spanning proteins (Oms) obtainable by the isolation and purification methods of the present invention.
Ellen S Shang from Calabasas, CA, age ~57 Get Report