Jason Edward Soares

8114679, Feb 14, 2012

Feb 11, 2008

12/079088

Diane M. Steeves - Franklin MA, US
Jason W. Soares - Shrewsbury MA, US

The United States of America as represented by the Secretary of the Army - Washington DC

G01N 21/76

436172, 257252, 257253, 257414

An optical biosensing platform for the real-time detection of the occurrence of a binding event, the optical biosensing platform comprising a nanocrystalline zinc oxide (nano-ZnO) substrate having a surface and being capable of emitting photoluminescence and a surface modifier formed integral with at least a portion of the surface of the nano-ZnO substrate, wherein the surface modifier is capable of binding to a biomolecule and wherein when the surface modifier binds with a biomolecule, a change is induced in the emitted photoluminescent properties of the nano-ZnO substrate, thereby enabling the detection of a binding event.

20040224358, Nov 11, 2004

May 23, 2002

10/153524

Charlene Mello - Rochester MA, US
Steven Arcidiacono - Bellingham MA, US
Jason Soares - Framingham MA, US

C12Q001/68
G01N033/53

435/007100, 435/006000

A method for discovering one or more peptides adapted for specific binding to a microorganism of interest. The method comprises (i) identifying an antimicrobial peptide having antimicrobial activity against the microorganism of interest, (ii) generating a library of first generation mutants of the antimicrobial peptide, each of the first generation mutants differing from the antimicrobial peptide by a small number of amino acid substitutions, additions or deletions, (iii) screening the library of first generation mutants for those first generation mutants that bind to the microorganism of interest, (iv) determining the peptide sequences of those first generation mutants that bind to the microorganism of interest, and (v) if necessary, repeating steps (ii) through (iv) for one or more successive generations of mutants until one or more consensus peptide sequences emerge.

20060148066, Jul 6, 2006

Jan 5, 2005

11/029548

Kris Senecal - North Smithfield RI, US
Andre Senecal - North Smithfield RI, US
Philip Pivarnik - Narragansett RI, US
Charlene Mello - Rochester MA, US
Jason Soares - Shrewsbury MA, US

C12M 1/34

435287200

A membrane assembly adapted for use in capturing an analyte of interest, the membrane assembly comprising in one embodiment (a) an electrospun nanofibrous membrane, the electrospun nanofibrous membrane comprising a random mat of electrospun nanofibers, at least some of the electrospun nanofibers including one or more types of functional groups; and (b) at least one molecular recognition element immobilized on the random mat via a functional group, the molecular recognition element being adapted to selectively bind the analyte of interest. The membrane assembly may be incorporated into a sensor.

20100240121, Sep 23, 2010

Mar 24, 2006

11/388175

Kris J. Senecal - North Smithfield RI, US
Andre G. Senecal - North Smithfield RI, US
Philip E. Pivarnik - Narragansett RI, US
Charlene M. Mello - Rochester MA, US
Jason W. Soares - Shrewsbury MA, US

C12M 1/34

4352872, 4352879

A membrane assembly adapted for use in capturing an analyte of interest, the membrane assembly comprising in one embodiment (a) an electrospun nanofibrous membrane, the electrospun nanofibrous membrane comprising a random mat of electrospun nanofibers, at least some of the electrospun nanofibers including one or more types of functional groups; and (b) at least one molecular recognition element immobilized on the random mat via a functional group, the molecular recognition element being adapted to selectively bind the analyte of interest. The membrane assembly may be incorporated into a sensor.