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Fiona Laird Hyland

from San Mateo, CA
Age ~59
Get Report
Also known as:
Fiona L Hyland, Fiona D Hyland, Fiona C Hyland, Fiona L Laird, Hyland Fiona Laird, Hyland F Laird, Fona Laird
Phone and address:
117 16Th Ave, San Mateo, CA 94402
Related to:
Leila M Laird, 34Theresa M Castro, 60Bernita A Gilmore, 81Evan JacksonSuede Tyler, 29
Connected to:
Anelia Hyland, 29Bonita J Hyland, 76Bryan P Hyland, 50Catherine H Hyland, 81Cori A Hyland, 56Dave R Hyland, 71Denis A Hyland, 57Doris E Hyland, 66Francis W Hyland, 79Jackie Hyland, 47

Fiona Hyland Phones & Addresses

  • 117 16Th Ave, San Mateo, CA 94402
  • Foster City, CA
  • Ithaca, NY
  • Burlingame, CA

Resumes

Resumes

Fiona Hyland Photo 1

Director R And D Informatics Clinical Next Generation Sequencing

Location:
262 Virginia Ave, San Mateo, CA 94402
Industry:
Biotechnology
Work:
Life Technologies since Jul 2012
Director of R&D, Ion Bioinformatics
Education:
Cornell University
Trinity Business School
Bachelors, Bachelor of Arts, Genetics
Skills:
Bioinformatics
Biotechnology
Dna Sequencing
Genetics
Sequencing
Genomics
Dna
Biostatistics
Genotyping
Life Sciences
R&D
Molecular Biology
Product Development
Data Analysis
Microarray
Lifesciences
Data Mining
Commercialization
Statistics
Software Project Management
Gene Expression
Assay Development
Competitive Analysis
Pcr
Technology Evaluation
Software Development
Algorithms
Drug Discovery
Project Management
Computational Biology
R
Technology Transfer
Cancer
Cell
Cross Functional Team Leadership
Population Genetics
Competitive Intelligence
Product Management
Perl
Biology
Cross Funct
Languages:
English
French
Fiona Hyland Photo 2

Fiona Hyland

Publications

Isbn (Books And Publications)

Feedback in Second Language Writing: Contexts and Issues

Author

Fiona Hyland

ISBN #

0521672589

Feedback in Second Language Writing: Contexts and Issues

Author

Fiona Hyland

ISBN #

0521856639

Us Patents

Systems And Methods For Identifying Exon Junctions From Single Reads

US Patent:
20110270532, Nov 3, 2011
Filed:
Apr 29, 2011
Appl. No.:
13/097328
Inventors:
Paolo VATTA - San Mateo CA, US
Onur Sakarya - Foster City CA, US
Heinz Breu - Palo Alto CA, US
Liviu Popescu - Sunnyvale CA, US
Asim Siddiqui - San Francisco CA, US
Fiona Hyland - San Mateo CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G06F 19/00
G01N 33/48
US Classification:
702 20
Abstract:
Systems and methods are used to identify an exon junction from a single read of a transcript. A transcript sample is interrogated and a read sequence is produced using a nucleic acid sequencer. A first exon sequence and a second exon sequence are obtained using the processor. The first exon sequence is mapped to a prefix of the read sequence using the processor. The second exon sequence is mapped to a suffix of the read sequence using the processor. A sum of a number of sequence elements of the first exon sequence that overlap the prefix of the read sequence, of a number of sequence elements of the second exon sequence that overlap the suffix of the read sequence, and of a constant is calculated using the processor. If the sum equals a length of the read sequence, a junction is identified in the read using the processor.

Systems And Methods For Sequence Data Alignment Quality Assessment

US Patent:
20120011086, Jan 12, 2012
Filed:
Jul 6, 2011
Appl. No.:
13/177267
Inventors:
Zheng ZHANG - Pasadena CA, US
Sowmi Utiramerur - Cupertino CA, US
Fiona Hyland - San Mateo CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G06N 3/02
US Classification:
706 20
Abstract:
A computer-implemented method for classifying alignments of paired nucleic acid sequence reads is disclosed. A plurality of paired nucleic acid sequence reads is received, wherein each read is comprised of a first tag and a second tag separated by an insert region. Potential alignments for the first and second tags of each read to a reference sequence is determined, wherein the potential alignments satisfies a minimum threshold mismatch constraint. Potential paired alignments of the first and second tags of each read are identified, wherein a distance between the first and second tags of each potential paired alignment is within an estimated insert size range. An alignment score is calculated for each potential paired alignment based on a distance between the first and second tags and a total number of mismatches for each tag.

Systems And Methods To Detect Copy Number Variation

US Patent:
20120046877, Feb 23, 2012
Filed:
Jul 5, 2011
Appl. No.:
13/176471
Inventors:
Fiona HYLAND - San Mateo CA, US
Rajesh Gottimukkala - Foster City CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G06F 19/00
US Classification:
702 20
Abstract:
In one aspect, a system for implementing a copy number variation analysis method, is disclosed. The system can include a nucleic acid sequencer and a computing device in communications with the nucleic acid sequencer. The nucleic acid sequencer can be configured to interrogate a sample to produce a nucleic acid sequence data file containing a plurality of nucleic acid sequence reads. In various embodiments, the computing device can be a workstation, mainframe computer, personal computer, mobile device, etc.The computing device can comprise a sequencing mapping engine, a coverage normalization engine, a segmentation engine and a copy number variation identification engine. The sequence mapping engine can be configured to align the plurality of nucleic acid sequence reads to a reference sequence, wherein the aligned nucleic acid sequence reads merge to form a plurality of chromosomal regions. The coverage normalization engine can be configured to divide each chromosomal region into one or more non-overlapping window regions, determine nucleic acid sequence read coverage for each window region and normalize the nucleic acid sequence read coverage determined for each window region to correct for bias. The segmentation engine can be configured to convert the normalized nucleic acid sequence read coverage for each window region to discrete copy number states. The copy number variation identification engine can be configured to identify copy number variation in the chromosomal regions by utilizing the copy number states of each window region.

Systems And Methods For Annotating Biomolecule Data

US Patent:
20120102054, Apr 26, 2012
Filed:
Oct 25, 2011
Appl. No.:
13/280990
Inventors:
Liviu POPESCU - Sunnyvale CA, US
Fiona Hyland - San Mateo CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G06F 17/30
US Classification:
707754, 707755, 707758, 707771, 707E17059, 707E17075
Abstract:
Systems, methods, software and computer-usable media for annotating biomolecule-related data are disclosed. In certain exemplified embodiments, the biomolecules can be nucleic acids and the data can be sequence-related data. In various embodiments, systems can include one or more public or private biological attributes (e.g., annotation information databases, data storage devices and systems, etc.) sources, one or more genomic features data sources (e.g., genomic variant tools, genomic variant databases, genomic variant data storage devices and systems, etc.), a computing device (e.g., workstation, server, personal computer, mobile device, etc.) hosting an annotations module and/or a reporting module, and a client terminal.

Systems And Methods For Mapping Sequence Reads

US Patent:
20120203792, Aug 9, 2012
Filed:
Feb 1, 2012
Appl. No.:
13/363717
Inventors:
Zheng ZHANG - Pasadena CA, US
Fiona HYLAND - San Mateo CA, US
Sowmi UTIRAMERUR - Cupertino CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G06F 17/30
US Classification:
707758, 707E17014
Abstract:
Systems, methods, and computer program products for aligning a fragment sequence to a target sequencing. The alignment is allowed at most one gap, such as an insertion or a deletion. In some embodiments, both a gapped alignment and an ungapped alignment can be produced. A selection can be made between the gapped alignment and the ungapped alignment based on a quality value for each alignment.

Systems And Methods For Identifying Sequence Variation

US Patent:
20130073214, Mar 21, 2013
Filed:
Sep 20, 2012
Appl. No.:
13/623709
Inventors:
Fiona HYLAND - San Mateo CA, US
Eric TSUNG - Needham MA, US
Vasisht TADIGOTLA - Brookline MA, US
Zheng ZHANG - Pasadena CA, US
Dumitru BRINZA - San Mateo CA, US
Onur SAKARYA - Redwood City CA, US
Xing XU - Chicago IL, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G06F 19/10
US Classification:
702 19
Abstract:
Systems and method for determining variants can receive mapped reads, and call variants. In embodiments, flow space information for the reads can be aligned to a flow space representation of a corresponding portion of the reference. Reads spanning a position with a potential variant can be grouped and a score can be calculated for the variant. Based on the scores, a list of probable variants can be provided. In various embodiments, low frequency variants can be identified where multiple potential variants are present at a position.

Systems And Methods For Analysis And Interpretation Of Nucleic Acid Sequence Data

US Patent:
20130091126, Apr 11, 2013
Filed:
Oct 10, 2012
Appl. No.:
13/648998
Inventors:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA, US
Srikanth JANDHYALA - Foster City CA, US
Yuandan LOU - Cupertino CA, US
Asim SIDDIQUI - San Francisco CA, US
Mrunal AGATE - Pune, IN
Ameet DHAPULKAR - Pune, IN
Heinz BREU - Palo Alto CA, US
Amitabh SHUKLA - San Jose CA, US
Karl KUHLMANN - Menlo Park CA, US
Fiona HYLAND - San Mateo CA, US
Gulsah ALTUN - Foster City CA, US
Daryl THOMAS - Menlo Park CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G06F 17/30
US Classification:
707722
Abstract:
Systems and method for annotating variants within a genome can call variants from reads or receive called variants directly and associate the called variants with functional annotations and interpretive annotations. A summary report of the called variants, the associated functional annotations, and the associated interpretive annotations can be generated.

Systems And Methods For Identifying Somatic Mutations

US Patent:
20130268207, Oct 10, 2013
Filed:
Mar 8, 2013
Appl. No.:
13/790713
Inventors:
Fiona HYLAND - San Mateo CA, US
Heinz BREU - Palo Alto CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
G06F 19/22
US Classification:
702 20
Abstract:
Systems and method for identifying somatic mutations can receive first ans second sequence information, determine if a variant present in the first sequencing information is also present in the second sequence information, and identify variants present in the first sequence information are somatic mutations when the variant is either not present in the second sequence information or the presence of the variant in the second sequence information is likely due to a sequencing error.
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Fiona Laird Hyland from San Mateo, CA, age ~59 Get Report