Inventors:
Arthur H. Neufeld - Chicago IL, US
Ai Ling Wang - Chicago IL, US
Assignee:
NORTHWESTERN UNIVERSITY - Evanston IL
International Classification:
A61K 39/00
A61P 27/02
A61P 37/04
Abstract:
Disclosed are compositions and methods for treating or preventing the formation of drusen in a patient in need thereof. The compositions include an effective amount of at least one polypeptide present in drusen, or an immunogenic fragment or variant thereof that induces an immune response against the polypeptide, together with a pharmaceutical carrier, excipient, or diluent. The compositions are suitable as vaccines for treating or preventing drusen and diseases associated with drusen.